To call this football game on Saturday the biggest game for each team is not much of a stretch.
The Iowa versus Iowa State rivalry dates back to 1894, but the two teams did not play each other from 1934 to 1977, the year the Cy-Hawk Trophy was established.
Throughout the 71-year history of the game, Iowa holds the all-time lead 47-24, but Iowa State has won two of the last three.
The No. 72 game in the series takes place at Jack Trice Stadium in Ames, Iowa, as both teams enter the game with undefeated records.
How to watch Iowa at Iowa State in Week Two
Date: September 6, 2025
Time: 11:00 a.m. Central Time
Venue: Jack Trice Stadium
How to watch (TV): Fox
Streaming: FuboTV
Iowa record: 1-0
Iowa State record: 2-0
Iowa at Iowa State odds, spread and total
Odds provided by FanDuel Sportsbook
Spread
- Iowa: +2.5 (+100)
- Iowa State: -2.5 (-122)
Moneyline
- Iowa: +126
- Iowa State: -152
Total
- Over/Under 42.5 (-110)
Iowa injuries
- Kamari Moulton (shoulder): Out
- Reece Vander Zee (foot): Out
- Bryce George (left arm): Out
Iowa State injuries
- N/A
Weather in Ames, Iowa
The weather will be hot for kickoff, with a temperature at nearly 84 degrees. There will be partly cloudy skies with a below 20 percent chance of precipitation at kickoff, with the chances increasing as the day goes on.
Rain and overall visibility should not be issues during the game, and the conditions should be great for afternoon football.
Announcers for Iowa at Iowa State
The Iowa at Iowa State game is the featured "Big Noon Kickoff" game on Fox, and the network has its top broadcast unit, featuring Gus Johnson (play-by-play), Joel Klatt (analyst), and Jenny Taft (sideline reporter) on the call.
Iowa versus Iowa State series history
The lastes iteration of the Iowa versus Iowa State Cy-Hawk rivalry will be No. 72 in the series. Iowa leads the all-time series 47-24, but Iowa State has won two of the last three. Iowa has won the previous six matchups in Ames.